Spleen locates at the deep end of the left hypochondriac, between the 9th and 11th ribs, and is the largest lymphoid organ in the human body. The spleen weight of children of all ages is between 10g and 113g, and is between 100g and 250g for the adults. The anatomy and function of spleen are closely associated with the liver and pancreas. Splenic artery, hepatic artery and left gastric artery are all from celiac axis. Splenic vein and superior mesenteric vein and inferior mesenteric vein jointly form the portal vein and then get into the liver. About 20 percent of the blood comes from the spleen. Spleen diseases are classified as spleen and hematopoietic system disease (thalassemia, spleen related inherited metabolic diseases, leukemia, etc.), infectious diseases (all kinds of specific and nonspecific infection), splenomegaly (portal hypertension, hypersplenism, etc.), splenic space-occupying lesions (spleen tumor, spleen cyst, etc.), spleen injury (spleen rupture, etc.), and some infrequent diseases (splenic infarction, wandering spleen, splenosis, etc.). Diagnosis of spleen diseases and selection of treatment are still a clinical difficulty.