This platform refers to other liver diseases, mainly related to congenital malformations (such as conjoined twins, acromphalus, gastroschisis, diaphragmatic hernia, mirror image, etc.), post-transplant liver, the tumor of liver adjacent organs (such as gastric cancer, transverse colon cancer, etc.), liver parasitic diseases, hereditary diseases (such as hepatolenticular degeneration), liver trauma, physical and chemical toxicity of liver injury and a variety of rare liver diseases. The factors such as a variety of etiology, scattered distribution and very low incidence cause diagnosis difficult, or even lead to delayed or wrong treatment. Even there is a clear diagnosis, complex anatomical physiology and limited knowledge make treatment extremely difficult. How to integrate large cases and explore the inherent laws of such diseases, is a difficulty placed in front of medical practitioners.
By using Computer Assisted Surgery System (CAS) to load liver diseases CT data set in format of DICOM, a transparent, visible and arbitrary three-dimensional digital model including liver parenchyma portal venous system and hepatic arterial system, hepatic vein and biliary system could be constructed. Thus the digital liver of an individualized liver diseases is formed. The digital liver is capable of presenting the functional liver volume and form of patients, the degree of damage to hepatic vascular system and biliary system, etc., which provides individualized clinical information for clinical diagnosis, liver function reserve evaluation, preoperative evaluation, treatment options selection, evaluation for liver transplantation and prognosis and offers individualized, accurate liver data for the treatment. The same three-dimensional construction based on the CT data set after the treatment in the same patient, compared different times with that before treatment, can help understand the impact of treatment and liver changes after treatment ,provide imaging support for further treatment, assess the prognosis of patients accurately and improve the clinical cure rate. Liver rare diseases of the bulky digital model can form an independent database for human research to provide valuable resources: The digital liver database of these diseases was established by digital model of homogeneous liver in the whole country and even the whole world. Then, the database was established according to the similar diseases, different stages of the same diseases and different age groups. The database can in a certain degree abandon uncertainties such as extremely rare diseases, clinical data incomplete and follow-up failure, improve the feasibility of diseases research. The analysis of the database is conducive to further understanding of the liver rare diseases in biological characteristics, epidemiological characteristics, treatment effect and the morphological changes of the liver after treatment, etc., then assess the impact of the lesion on the body and the near-long-term effects of treatment, analysis of the cause, which will provide intuitive, adequate and effective clinical digital data for our study in pathophysiology, therapeutics, etiology and infancy development.
